Description
Ovu-Mate Indications
Altrenogest acts similarly to the natural hormone, progesterone, by suppressing the normal oestrus cycle and preventing signs of
heat and ovulation. Mares return to heat and release natural hormones again once treatment stops. Treatment with altrenogest
makes it possible to regulate the breeding of mares.
Ovu-Mate injection may be used in fillies and mares to:
• Delay the onset of oestrus
• Suppress oestrous behaviour
Pharmacology
Pharmacokinetic data from mares treated with Ovu-Mate, have shown blood levels of altrenogest are maintained for 5 days
following administration of the injection. Studies have been conducted to support suppression of behavioural signs of oestrus in
cycling mares for 7 days following administration of Altrenogest Injection.
Although weekly Ovu-Mate injections have been used for the maintenance of pregnancy in habitually aborting mares, its use in the
maintenance of pregnancy has not yet been established in clinical trials.
Contraindications
This product is contraindicated for use in stallions and geldings. Ovu-Mate use in pregnant mares has not been established.
Precautions
There is evidence that when progestagens are administered to rats during the embryonic stage of pregnancy at doses higher
than the recommended equine dose, foetal abnormalities (specifically masculinisation of female genitalia) can result. If used in
performance animals, the regulations of the relevant authorities regarding medication should be observed.
Safety Directions
Care should be taken to avoid contact between the solution and women of child bearing age. Product is harmful if absorbed
by skin contact or inhaled or swallowed. Avoid contact with eyes and skin. Do not inhale. When using the product wear rubber
gloves. After use and before eating, drinking or smoking, wash hands, arms and face thoroughly with soap and water. After each
day’s use wash gloves.
Additional User Safety: Warning: Suspected of damaging infertility or the unborn child. Women who are pregnant or suspected
of being pregnant should not handle the product. Women of childbearing age should handle the product with extreme care. Not to
be handled by persons with known or suspected progesterone dependent tumours or thromboembolic disorders.
Meat Withholding Period: NOT TO BE USED in horses that may be used for human consumption.
Racing/Event Withholding Period: If used in performance animals, the regulations of the relevant authorities regarding
medication should be observed.
Disposal: Dispose of empty container by wrapping with paper and putting in garbage.
Storage: Store below 25°C (Air Conditioning). Store in an upright position. Protect from light.
Discard unused portion within 28 days of first broaching of vial.
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